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Your query returned 9 entries. Printable version
EC | 1.1.1.290 | ||||||||||||
Accepted name: | 4-phosphoerythronate dehydrogenase | ||||||||||||
Reaction: | 4-phospho-D-erythronate + NAD+ = (3R)-3-hydroxy-2-oxo-4-phosphooxybutanoate + NADH + H+ | ||||||||||||
For diagram of pyridoxal biosynthesis, click here | |||||||||||||
Other name(s): | PdxB; PdxB 4PE dehydrogenase; 4-O-phosphoerythronate dehydrogenase; 4PE dehydrogenase; erythronate-4-phosphate dehydrogenase | ||||||||||||
Systematic name: | 4-phospho-D-erythronate:NAD+ 2-oxidoreductase | ||||||||||||
Comments: | This enzyme catalyses a step in a bacterial pathway for the biosynthesis of pyridoxal 5′-phosphate. The enzyme contains a tightly-bound NAD(H) cofactor that is not re-oxidized by free NAD+. In order to re-oxidize the cofactor and restore enzyme activity, the enzyme catalyses the reduction of a 2-oxo acid (such as 2-oxoglutarate, oxaloacetate, or pyruvate) to the respective (R)-hydroxy acid [6]. cf. EC 1.1.1.399, 2-oxoglutarate reductase. | ||||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 125858-75-5 | ||||||||||||
References: |
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EC | 1.1.1.408 | ||||||||||||
Accepted name: | 4-phospho-D-threonate 3-dehydrogenase | ||||||||||||
Reaction: | 4-phospho-D-threonate + NAD+ = glycerone phosphate + CO2 + NADH + H+ (overall reaction) (1a) 4-phospho-D-threonate + NAD+ = 3-dehydro-4-phospho-D-erythronate + NADH + H+ (1b) 3-dehydro-4-phospho-D-erythronate = glycerone phosphate + CO2 (spontaneous) |
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For diagram of erythronate and threonate catabolism, click here | |||||||||||||
Glossary: | D-threonate = (2S,3R)-2,3,4-trihydroxybutanoate glycerone phosphate = dihydroxyacetone phosphate = 3-hydroxy-2-oxopropyl phosphate |
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Other name(s): | pdxA2 (gene name) (ambiguous) | ||||||||||||
Systematic name: | 4-phospho-D-threonate:NAD+ 3-oxidoreductase | ||||||||||||
Comments: | The enzyme, characterized from bacteria, is involved in a pathway for D-threonate catabolism. | ||||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB | ||||||||||||
References: |
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EC | 1.1.1.409 | ||||||||||||
Accepted name: | 4-phospho-D-erythronate 3-dehydrogenase | ||||||||||||
Reaction: | 4-phospho-D-erythronate + NAD+ = glycerone phosphate + CO2 + NADH + H+ (overall reaction) (1a) 4-phospho-D-erythronate + NAD+ = 3-dehydro-4-phospho-L-threonate + NADH + H+ (1b) 3-dehydro-4-phospho-L-threonate = glycerone phosphate + CO2 (spontaneous) |
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For diagram of erythronate and threonate catabolism, click here | |||||||||||||
Glossary: | D-erythronate = (2R,3R)-2,3,4-trihydroxybutanoate | ||||||||||||
Other name(s): | pdxA2 (gene name) (ambiguous) | ||||||||||||
Systematic name: | 4-phospho-D-erythronate:NAD+ 3-oxidoreductase | ||||||||||||
Comments: | The enzyme, characterized from bacteria, is involved in a pathway for D-erythronate catabolism. | ||||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||||||||
References: |
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EC | 1.1.1.410 | ||||||||||||
Accepted name: | D-erythronate 2-dehydrogenase | ||||||||||||
Reaction: | D-erythronate + NAD+ = 2-dehydro-D-erythronate + NADH + H+ | ||||||||||||
For diagram of erythronate and threonate catabolism, click here | |||||||||||||
Glossary: | D-erythronate = (2R,3R)-2,3,4-trihydroxybutanoate 2-dehydro-D-erythronate = (3R)-3,4-dihydroxy-2-oxobutanoate |
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Other name(s): | denD (gene name) | ||||||||||||
Systematic name: | D-erythronate:NAD+ 2-oxidoreductase | ||||||||||||
Comments: | The enzyme, characterized from bacteria, is involved in D-erythronate catabolism. | ||||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||||||||
References: |
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EC | 2.7.1.217 | ||||||||||||
Accepted name: | 3-dehydrotetronate 4-kinase | ||||||||||||
Reaction: | (1) ATP + 3-dehydro-L-erythronate = ADP + 3-dehydro-4-phospho-L-erythronate (2) ATP + 3-dehydro-D-erythronate = ADP + 3-dehydro-4-phospho-D-erythronate |
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For diagram of erythronate and threonate catabolism, click here | |||||||||||||
Glossary: | L-erythronate = (2S,3S)-2,3,4-trihydroxybutanoate D-erythronate = (2R,3R)-2,3,4-trihydroxybutanoate |
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Other name(s): | otnK (gene name) | ||||||||||||
Systematic name: | ATP:3-dehydrotetronate 4-phosphotransferase | ||||||||||||
Comments: | The enzyme, characterized from bacteria, is involved in D-erythronate and L-threonate catabolism. | ||||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB | ||||||||||||
References: |
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EC | 2.7.1.220 | ||||||||||||
Accepted name: | D-erythronate 4-kinase | ||||||||||||
Reaction: | ATP + D-erythronate = ADP + 4-phospho-D-erythronate | ||||||||||||
Glossary: | D-erythronate = (2R,3R)-2,3,4-trihydroxybutanoate | ||||||||||||
Other name(s): | denK (gene name) | ||||||||||||
Systematic name: | ATP:D-erythronate 4-phosphotransferase | ||||||||||||
Comments: | The enzyme, characterized from bacteria, is involved in a pathway for D-erythronate catabolism. | ||||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||||||||
References: |
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EC | 4.1.1.104 | ||||||||||||
Accepted name: | 3-dehydro-4-phosphotetronate decarboxylase | ||||||||||||
Reaction: | (1) 3-dehydro-4-phospho-L-erythronate = glycerone phosphate + CO2 (2) 3-dehydro-4-phospho-D-erythronate = glycerone phosphate + CO2 |
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For diagram of erythronate and threonate catabolism, click here | |||||||||||||
Glossary: | L-erythronate = (2S,3S)-2,3,4-trihydroxybutanoate D-erythronate = (2R,3R)-2,3,4-trihydroxybutanoate |
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Other name(s): | otnC (gene name) | ||||||||||||
Systematic name: | 3-dehydro-4-phosphotetronate carboxy-lyase | ||||||||||||
Comments: | The enzyme, characterized from bacteria, is involved in D-erythronate and L-threonate catabolism. | ||||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB | ||||||||||||
References: |
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EC | 4.2.1.11 | ||||||||||||
Accepted name: | phosphopyruvate hydratase | ||||||||||||
Reaction: | 2-phospho-D-glycerate = phosphoenolpyruvate + H2O | ||||||||||||
For diagram of the Entner-Doudoroff pathway, click here | |||||||||||||
Other name(s): | enolase; 2-phosphoglycerate dehydratase; 14-3-2-protein; nervous-system specific enolase; phosphoenolpyruvate hydratase; 2-phosphoglycerate dehydratase; 2-phosphoglyceric dehydratase; 2-phosphoglycerate enolase; γ-enolase; 2-phospho-D-glycerate hydro-lyase | ||||||||||||
Systematic name: | 2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming) | ||||||||||||
Comments: | Also acts on 3-phospho-D-erythronate. | ||||||||||||
Links to other databases: | BRENDA, EXPASY, GTD, KEGG, MetaCyc, PDB, CAS registry number: 9014-08-8 | ||||||||||||
References: |
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EC | 5.3.1.35 | ||||||||||||
Accepted name: | 2-dehydrotetronate isomerase | ||||||||||||
Reaction: | (1) 2-dehydro-L-erythronate = 3-dehydro-L-erythronate (2) 2-dehydro-D-erythronate = 3-dehydro-D-erythronate |
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For diagram of erythronate and threonate catabolism, click here | |||||||||||||
Glossary: | L-erythronate = (2S,3S)-2,3,4-trihydroxybutanoate D-erythronate = (2R,3R)-2,3,4-trihydroxybutanoate |
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Other name(s): | otnI (gene name) | ||||||||||||
Systematic name: | 2-dehydrotetronate isomerase | ||||||||||||
Comments: | The enzyme, characterized from bacteria, is involved in D-erythronate and L-threonate catabolism. | ||||||||||||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB | ||||||||||||
References: |
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