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Your query returned 1 entry. Printable version
EC | 1.14.19.37 | ||
Accepted name: | acyl-CoA 5-desaturase | ||
Reaction: | (1) (11Z,14Z)-icosa-11,14-dienoyl-CoA + reduced acceptor + O2 = (5Z,11Z,14Z)-icosa-5,11,14-trienoyl-CoA + acceptor + 2 H2O (2) (11Z,14Z,17Z)-icosa-11,14,17-trienoyl-CoA + reduced acceptor + O2 = (5Z,11Z,14Z,17Z)-icosa-5,11,14,17-tetraenoyl-CoA + acceptor + 2 H2O |
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Glossary: | (5Z,11Z,14Z)-icosa-5,11,14-trienoate = sciadonate (5Z,11Z,14Z,17Z)-icosa-5,11,14,17-tetraenoate = juniperonate |
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Other name(s): | acyl-CoA 5-desaturase (non-methylene-interrupted) | ||
Systematic name: | acyl-CoA,acceptor:oxygen oxidoreductase (5,6 cis-dehydrogenating) | ||
Comments: | The enzyme, characterized from the plant Anemone leveillei, introduces a cis double bond at carbon 5 of acyl-CoAs that do not contain a double bond at position 8. In vivo it forms non-methylene-interrupted polyunsaturated fatty acids such as sciadonate and juniperonate. When expressed in Arabidopsis thaliana the enzyme could also act on unsaturated substrates such as palmitoyl-CoA. cf. EC 1.14.19.44, acyl-CoA (8-3)-desaturase. | ||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||
References: |
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