EC 7.6.2.5     
Accepted name: ABC-type heme transporter
Reaction: ATP + H2O + heme[side 1] = ADP + phosphate + heme[side 2]
Other name(s): heme-transporting ATPase
Systematic name: ATP phosphohydrolase (ABC-type, heme-exporting)
Comments: An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. Does not undergo phosphorylation during the transport process. The enzyme has been described from Gram-negative bacteria and green plants.
References:
1.  Ramseier, T.M., Winteler, H.V. and Hennecke, H. Discovery and sequence analysis of bacterial genes involved in the biogenesis of c-type cytochromes. J. Biol. Chem. 266 (1991) 7793–7803. [PMID: 1850420]
2.  Jekabsons, W. and Schuster, W. orf250 encodes a second subunit of an ABC-type heme transporter in Oenothera mitochondria. Mol. Gen. Genet. 246 (1995) 166–173. [PMID: 7862087]
3.  Saier, M.H., Jr. Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya. Adv. Microb. Physiol. 40 (1998) 81–136. [PMID: 9889977]
[EC 7.6.2.5 created 2000 as EC 3.6.3.41, transferred 2018 to EC 7.6.2.5]
 
 


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