The Enzyme Database

Your query returned 1 entry.    printer_iconPrintable version

EC 7.3.2.2     
Accepted name: ABC-type phosphonate transporter
Reaction: ATP + H2O + phosphonate-[phosphonate-binding protein][side 1] = ADP + phosphate + phosphonate[side 2] + [phosphonate-binding protein][side 1]
Other name(s): phosphonate-transporting ATPase (ambiguous)
Systematic name: ATP phosphohydrolase (ABC-type, phosphonate-importing)
Comments: An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. The enzyme, found in bacteria, interacts with an extracytoplasmic substrate binding protein and mediates the import of phosphonate and organophosphate anions.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Wanner, B.L. and Metcalf, W.W. Molecular genetic studies of a 10.9-kb operon in Escherichia coli for phosphonate uptake and biodegradation. FEMS Microbiol. Lett. 79 (1992) 133–139. [PMID: 1335942]
2.  Kuan, G., Dassa, E., Saurin, N., Hofnung, M. and Saier, M.H., Jr. Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases. Res. Microbiol. 146 (1995) 271–278. [DOI] [PMID: 7569321]
3.  Saier, M.H., Jr. Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya. Adv. Microb. Physiol. 40 (1998) 81–136. [PMID: 9889977]
4.  Griffiths, J.K. and Sansom, C.E. The Transporter Factsbook, Academic Press, San Diego, 1998.
[EC 7.3.2.2 created 2000 as EC 3.6.3.28, transferred 2018 to EC 7.3.2.2]
 
 


Data © 2001–2019 IUBMB
Web site © 2005–2019 Andrew McDonald