| EC |
7.2.2.5 |
| Accepted name: |
ABC-type Mn2+ transporter |
| Reaction: |
ATP + H2O + Mn2+-[manganese-binding protein][side 1] = ADP + phosphate + Mn2+[side 2] + [manganese-binding protein][side 1] |
| Other name(s): |
ABC-type manganese permease complex; manganese-transporting ATPase (ambiguous); ABC-type manganese transporter |
| Systematic name: |
ATP phosphohydrolase (ABC-type, Mn2+-importing) |
| Comments: |
ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains. A bacterial enzyme that interacts with an extracytoplasmic substrate binding protein and mediates the import of Mn2+, Zn2+ and iron chelates. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Kuan, G., Dassa, E., Saurin, N., Hofnung, M. and Saier, M.H., Jr. Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases. Res. Microbiol. 146 (1995) 271–278. [DOI] [PMID: 7569321] |
| 2. |
Saier, M.H., Jr. Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya. Adv. Microb. Physiol. 40 (1998) 81–136. [PMID: 9889977] |
| 3. |
Novak, R., Braun, J.S., Charpentier, E. and Tuomanen, E. Penicillin tolerance genes of Streptococcus pneumoniae: the ABC-type manganese permease complex Psa. Mol. Microbiol. 29 (1998) 1285–1296. [DOI] [PMID: 9767595] |
| 4. |
Kolenbrander, P.E., Andersen, R.N., Baker, R.A. and Jenkinson, H.F. The adhesion-assoiated aca operon in Streptococcus gordonii encodes an inducible high-affinity ABC transporter for Mn2+ uptake. J. Bacteriol. 180 (1998) 290–295. [PMID: 9440518] |
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| [EC 7.2.2.5 created 2000 as EC 3.6.3.35, transferred 2018 to EC 7.2.2.5] |
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