| EC |
6.4.1.8 |
| Accepted name: |
acetophenone carboxylase |
| Reaction: |
2 ATP + acetophenone + HCO3- + H2O + H+ = 2 ADP + 2 phosphate + 3-oxo-3-phenylpropanoate |
| Systematic name: |
acetophenone:carbon-dioxide ligase (ADP-forming) |
| Comments: |
The enzyme is involved in anaerobic degradation of ethylbenzene. No activity with acetone, butanone, 4-hydroxy-acetophenone or 4-amino-acetophenone. |
| Links to other databases: |
BRENDA, EAWAG-BBD, EXPASY, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Jobst, B., Schuhle, K., Linne, U. and Heider, J. ATP-dependent carboxylation of acetophenone by a novel type of carboxylase. J. Bacteriol. 192 (2010) 1387–1394. [DOI] [PMID: 20047908] |
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| [EC 6.4.1.8 created 2011] |
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