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Your query returned 1 entry. 
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| EC | 6.4.1.10 | ||||||
| Accepted name: | atromentin synthase | ||||||
| Reaction: | 2 ATP + 2 3-(4-hydroxyphenyl)pyruvate = 2 AMP + 2 diphosphate + atromentin (overall reaction) (1a) ATP + 3-(4-hydroxyphenyl)pyruvate + [atromentin synthase] = AMP + diphosphate + 3-(4-hydroxyphenyl)pyruvoyl-[atromentin synthase] (1b) ATP + 3-(4-hydroxyphenyl)pyruvate + 3-(4-hydroxyphenyl)pyruvoyl-[atromentin synthase] = AMP + diphosphate + atromentin + [atromentin synthase] |
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| Glossary: | atromentin = 2,5-dihydroxy-3,6-bis(4-hydroxyphenyl)-1,4-benzoquinone | ||||||
| Other name(s): | atromentin synthetase; invA1 (gene name); invA2 (gene name); invA5 (gene name); greA (gene name); atrA (gene name) | ||||||
| Systematic name: | 3-(4-hydroxyphenyl)pyruvate:3-(4-hydroxyphenyl)pyruvate ligase (atromentin-forming) | ||||||
| Comments: | Requires Mg2+.The enzyme, found in some fungi such as members of the Boletales and Eurotiales order, is a non-ribosomal peptide synthase-like enzyme comprising three domains - an adelylation (A) domain, an ayl-carrier protein (ACP) domain, and a thioesterase (TE) domain. The enzyme activates 3-(4-hydroxyphenyl)pyruvate by adenylation and catalyses the dimerization/cyclization of two such molecules to form atromentin. Atromentin is a precursor for assorted metabolites produced by the fungi, including pulvinic acids and 2,5-diarylcyclopentenones. | ||||||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||||||
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