The Enzyme Database

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Accepted name: ribose-5-phosphate—ammonia ligase
Reaction: ATP + ribose 5-phosphate + NH3 = ADP + phosphate + 5-phosphoribosylamine
For diagram of ribose activation, click here
Other name(s): 5-phosphoribosylamine synthetase; ribose 5-phosphate aminotransferase; ammonia-ribose 5-phosphate aminotransferase
Systematic name: ribose-5-phosphate:ammonia ligase (ADP-forming)
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 9082-52-4
1.  Reem, G.H. Enzymatic synthesis of 5′-phosphoribosylamine from ribose 5-phosphate and ammonia, an alternate first step in purine biosynthesis. J. Biol. Chem. 243 (1968) 5695–5701. [PMID: 5699059]
[EC created 1972]

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