The Enzyme Database

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Accepted name: dethiobiotin synthase
Reaction: ATP + 7,8-diaminononanoate + CO2 = ADP + phosphate + dethiobiotin
Other name(s): desthiobiotin synthase
Systematic name: 7,8-diaminononanoate:carbon-dioxide cyclo-ligase (ADP-forming)
Comments: CTP has half the activity of ATP.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 37259-75-9
1.  Krell, K. and Eisenberg, M.A. The purification and properties of dethiobiotin synthetase. J. Biol. Chem. 245 (1970) 6558–6566. [PMID: 4921568]
2.  Yang, H.-C., Tani, Y. and Ogata, K. Synthesis of biotin vitamers from biotin diaminocarboxylic acid or 7,8-diaminopelargonic acid by a purified enzyme of Pseudomonas graveolens. Agric. Biol. Chem. 34 (1970) 1748–1750.
[EC created 1976]

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