| EC |
6.3.3.3 |
| Accepted name: |
dethiobiotin synthase |
| Reaction: |
ATP + 7,8-diaminononanoate + CO2 = ADP + phosphate + dethiobiotin |
| Other name(s): |
desthiobiotin synthase |
| Systematic name: |
7,8-diaminononanoate:carbon-dioxide cyclo-ligase (ADP-forming) |
| Comments: |
CTP has half the activity of ATP. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 37259-75-9 |
| References: |
| 1. |
Krell, K. and Eisenberg, M.A. The purification and properties of dethiobiotin synthetase. J. Biol. Chem. 245 (1970) 6558–6566. [PMID: 4921568] |
| 2. |
Yang, H.-C., Tani, Y. and Ogata, K. Synthesis of biotin vitamers from biotin diaminocarboxylic acid or 7,8-diaminopelargonic acid by a purified enzyme of Pseudomonas graveolens. Agric. Biol. Chem. 34 (1970) 1748–1750. |
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| [EC 6.3.3.3 created 1976] |
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