The Enzyme Database

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Accepted name: 5-formyltetrahydrofolate cyclo-ligase
Reaction: ATP + 5-formyltetrahydrofolate = ADP + phosphate + 5,10-methenyltetrahydrofolate
For diagram of folate cofactors, click here and for diagram of C1 metabolism, click here
Other name(s): 5,10-methenyltetrahydrofolate synthetase; formyltetrahydrofolic cyclodehydrase; 5-formyltetrahydrofolate cyclodehydrase
Systematic name: 5-formyltetrahydrofolate cyclo-ligase (ADP-forming)
Links to other databases: BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 37318-64-2
1.  Greenberg, D.M., Wynston, L.K. and Nagabhushanan, A. Further studies on N5-formyltetrahydrofolic acid cyclodehydrase. Biochemistry 4 (1965) 1872–1878.
[EC created 1972]

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