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Your query returned 1 entry. Printable version
EC | 6.3.1.22 | ||
Accepted name: | tRNAmet cytidine acetate ligase | ||
Reaction: | ATP + [elongator tRNAMet]-cytidine34 + acetate = AMP + diphosphate + [elongator tRNAMet]-N4-acetylcytidine34 (overall reaction) (1a) ATP + acetate = acetyladenylate + diphosphate (1b) acetyladenylate + [elongator tRNAMet]-cytidine34 = AMP + [elongator tRNAMet]-N4-acetylcytidine34 |
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Other name(s): | tmcAL (gene name) | ||
Systematic name: | elongator tRNAmet cytidine:acetate ligase (AMP-forming) | ||
Comments: | The enzyme, charactrized from the bacterium Bacillus subtilis, catalyses a similar tRNA modification to that performed by EC 2.3.1.193, tRNAMet cytidine acetyltransferase. However, unlike that enzyme, which uses acetyl-CoA as the acetyl donor, this enzyme activates an acetate ion to form acetyladenylate and then catalyses the acetylation through a mechanism similar to tRNA aminoacylation. | ||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB | ||
References: |
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