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Your query returned 1 entry. 
Printable version
| EC | 6.2.1.69 | ||
| Accepted name: | L-cysteine—[L-cysteinyl-carrier protein] ligase | ||
| Reaction: | ATP + L-cysteine + holo-[L-cysteinyl-carrier protein] = AMP + diphosphate + L-cysteinyl-[L-cysteinyl-carrier protein] (overall reaction) (1a) ATP + L-cysteine = diphosphate + (L-cysteinyl)adenylate (1b) (L-cysteinyl)adenylate + holo-[L-cysteinyl-carrier protein] = AMP + L-cysteinyl-[L-cysteinyl-carrier protein] |
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| Other name(s): | pchE (gene name); pchF (gene name); angR (gene name) | ||
| Systematic name: | L-cysteine:[L-cysteinyl-carrier protein] ligase (AMP-forming) | ||
| Comments: | The adenylation domain of the enzyme catalyses the activation of L-cysteine to (L-cysteinyl)adenylate, followed by the transfer of the activated compound to the free thiol of a phosphopantetheine arm of a peptidyl-carrier protein domain. The peptidyl-carrier protein domain may be part of the same protein, or of a different protein. This activity is often found as part of a larger non-ribosomal peptide synthase. | ||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, PDB | ||
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