EC |
6.2.1.25 |
Accepted name: |
benzoate—CoA ligase |
Reaction: |
ATP + benzoate + CoA = AMP + diphosphate + benzoyl-CoA |
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For diagram of Benzoyl-CoA catabolism, click here |
Other name(s): |
benzoate—coenzyme A ligase; benzoyl-coenzyme A synthetase; benzoyl CoA synthetase (AMP forming) |
Systematic name: |
benzoate:CoA ligase (AMP-forming) |
Comments: |
Also acts on 2-, 3- and 4-fluorobenzoate, but only very slowly on the corresponding chlorobenzoates. |
Links to other databases: |
BRENDA, EAWAG-BBD, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 95329-17-2 |
References: |
1. |
Hutber, G.N. and Ribbons, D.W. Involvement of coenzyme-A esters in the metabolism of benzoate and cyclohexanecarboxylate by Rhodopseudomonas palustris. J. Gen. Microbiol. 129 (1983) 2413–2420. |
2. |
Schennen, U., Braun, K. and Knackmuss, H.-J. Anaerobic degradation of 2-fluorobenzoate by benzoate-degrading, denitrifying bacteria. J. Bacteriol. 161 (1985) 321–325. [PMID: 2857161] |
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[EC 6.2.1.25 created 1989] |
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