| EC |
6.2.1.23 |
| Accepted name: |
dicarboxylate—CoA ligase |
| Reaction: |
ATP + an α,ω-dicarboxylate + CoA = AMP + diphosphate + an ω-carboxyacyl-CoA |
| Other name(s): |
carboxylyl-CoA synthetase; dicarboxylyl-CoA synthetase |
| Systematic name: |
ω-dicarboxylate:CoA ligase (AMP-forming) |
| Comments: |
Acts on dicarboxylic acids of chain length C5 to C16; the best substrate is dodecanedioic acid. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, CAS registry number: 99332-77-1 |
| References: |
| 1. |
Vamecq, J., de Hoffmann, E. and van Hoof, F. The microsomal dicarboxylyl-CoA synthetase. Biochem. J. 230 (1985) 683–693. [PMID: 4062873] |
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| [EC 6.2.1.23 created 1989, modified 2011] |
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