EC |
6.2.1.18 |
Accepted name: |
citrate—CoA ligase |
Reaction: |
ATP + citrate + CoA = ADP + phosphate + (3S)-citryl-CoA |
Glossary: |
citrate = 2-hydroxypropane-1,2,3-tricarboxylate |
Other name(s): |
citryl-CoA synthetase; citrate:CoA ligase; citrate thiokinase |
Systematic name: |
citrate:CoA ligase (ADP-forming) |
Comments: |
The enzyme is a component of EC 2.3.3.8 ATP citrate synthase. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 856428-87-0 |
References: |
1. |
Lill, U., Schreil, A. and Eggerer, H. Isolation of enzymically active fragments formed by limited proteolysis of ATP citrate lyase. Eur. J. Biochem. 125 (1982) 645–650. [DOI] [PMID: 6749502] |
2. |
Aoshima, M., Ishii, M. and Igarashi, Y. A novel enzyme, citryl-CoA synthetase, catalysing the first step of the citrate cleavage reaction in Hydrogenobacter thermophilus TK-6. Mol. Microbiol. 52 (2004) 751–761. [DOI] [PMID: 15101981] |
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[EC 6.2.1.18 created 1986] |
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