The Enzyme Database

Your query returned 1 entry.    printer_iconPrintable version

Accepted name: acetate—CoA ligase
Reaction: ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA
Other name(s): acetyl-CoA synthetase; acetyl activating enzyme; acetate thiokinase; acyl-activating enzyme; acetyl coenzyme A synthetase; acetic thiokinase; acetyl CoA ligase; acetyl CoA synthase; acetyl-coenzyme A synthase; short chain fatty acyl-CoA synthetase; short-chain acyl-coenzyme A synthetase; ACS
Systematic name: acetate:CoA ligase (AMP-forming)
Comments: Also acts on propanoate and propenoate.
Links to other databases: BRENDA, EXPASY, GTD, KEGG, MetaCyc, PDB, CAS registry number: 9012-31-1
1.  Chou, T.C. and Lipmann, F. Separation of acetyl transfer enzymes in pigeon liver extract. J. Biol. Chem. 196 (1952) 89–103. [PMID: 12980945]
2.  Eisenberg, M.A. The acetate-activating enzyme of Rhodospirillum rubrum. Biochim. Biophys. Acta 16 (1955) 58–65. [DOI] [PMID: 14363230]
3.  Hele, P. The acetate activating enzyme of beef heart. J. Biol. Chem. 206 (1954) 671–676. [PMID: 13143026]
4.  Millerd, A. and Bonner, J. Acetate activation and acetoacetate formation in plant systems. Arch. Biochem. Biophys. 49 (1954) 343–355. [DOI] [PMID: 13159282]
[EC created 1961]

Data © 2001–2024 IUBMB
Web site © 2005–2024 Andrew McDonald