EC |
5.4.99.4 |
Accepted name: |
2-methyleneglutarate mutase |
Reaction: |
2-methyleneglutarate = 2-methylene-3-methylsuccinate |
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For diagram of nicotinate catabolism, click here |
Other name(s): |
α-methyleneglutarate mutase |
Systematic name: |
2-methyleneglutarate carboxy-methylenemethylmutase |
Comments: |
Requires a cobamide cofactor. |
Links to other databases: |
BRENDA, EXPASY, GTD, KEGG, MetaCyc, CAS registry number: 9059-10-3 |
References: |
1. |
Kung, H.-F., Cederbaum, S., Tsai, L. and Stadtman, T.C. Nicotinic acid metabolism. V. A cobamide coenzyme-dependent conversion of α-methyleneglutaric acid to dimethylmaleic acid. Proc. Natl. Acad. Sci. USA 65 (1970) 978–984. [DOI] [PMID: 5266166] |
2. |
Kung, H.-F. and Stadtman, T.C. Nicotinic acid metabolism. VI. Purification and properties of α-methyleneglutarate mutase (B12-dependent) and methylitaconate isomerase. J. Biol. Chem. 246 (1971) 3378–3388. [PMID: 5574401] |
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[EC 5.4.99.4 created 1972] |
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