EC |
5.4.99.38 |
Accepted name: |
camelliol C synthase |
Reaction: |
(3S)-2,3-epoxy-2,3-dihydrosqualene = camelliol C |
Other name(s): |
CAMS1; LUP3 (gene name) |
Systematic name: |
(3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, camelliol-C-forming) |
Comments: |
The product is 97% camelliol, 2% achilleol A and 0.2% β-amyrin. Achilleol is an isomer of camelliol C with a 4-methylenecyclohexanol ring system. This enzyme probably evolved from EC 5.4.99.39, β-amyrin synthase. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Kolesnikova, M.D., Wilson, W.K., Lynch, D.A., Obermeyer, A.C. and Matsuda, S.P. Arabidopsis camelliol C synthase evolved from enzymes that make pentacycles. Org. Lett. 9 (2007) 5223–5226. [DOI] [PMID: 17985917] |
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[EC 5.4.99.38 created 2011] |
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