ExplorEnz: EC 5.4.99.20

5.4.99.20

Accepted name:

23S rRNA pseudouridine²⁴⁵⁷ synthase

Reaction:

23S rRNA uridine²⁴⁵⁷ = 23S rRNA pseudouridine²⁴⁵⁷

Other name(s):

RluE; YmfC

Systematic name:

23S rRNA-uridine²⁴⁵⁷ uracil mutase

Comments:

The enzyme modifies uridine²⁴⁵⁷ in a stem of 23S RNA in Escherichia coli.

References:

1.	Del Campo, M., Kaya, Y. and Ofengand, J. Identification and site of action of the remaining four putative pseudouridine synthases in Escherichia coli. RNA 7 (2001) 1603–1615. [PMID: 11720289]
2.	Pan, H., Ho, J.D., Stroud, R.M. and Finer-Moore, J. The crystal structure of E. coli rRNA pseudouridine synthase RluE. J. Mol. Biol. 367 (2007) 1459–1470. [PMID: 17320904]

[EC 5.4.99.20 created 2011]