Accepted name: lutein isomerase
Reaction: lutein = meso-zeaxanthin
Glossary: lutein = (3R,3′R)-dihydroxy-α-carotene
meso-zeaxanthin = (3R,3′S)-β,β-carotene-3,3′-diol
Other name(s): RPE65 (gene name); meso-zeaxanthin isomerase
Systematic name: lutein Δ45-isomerase
Comments: The enzyme is found in the retinal pigment epithelium (RPE) of vertebrates. It also has the activity of EC, retinoid isomerohydrolase.
1.  Shyam, R., Gorusupudi, A., Nelson, K., Horvath, M.P. and Bernstein, P.S. RPE65 has an additional function as the lutein to meso-zeaxanthin isomerase in the vertebrate eye. Proc. Natl. Acad. Sci. USA 114 (2017) 10882–10887. [PMID: 28874556]
[EC created 2018]

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