| EC |
5.2.1.2 |
| Accepted name: |
maleylacetoacetate isomerase |
| Reaction: |
4-maleylacetoacetate = 4-fumarylacetoacetate |
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For diagram of tyrosine catabolism, click here |
| Other name(s): |
maleylacetoacetic isomerase; maleylacetone isomerase; maleylacetone cis-trans-isomerase |
| Systematic name: |
4-maleylacetoacetate cis-trans-isomerase |
| Comments: |
Also acts on maleylpyruvate. |
| Links to other databases: |
BRENDA, EAWAG-BBD, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 9023-75-0 |
| References: |
| 1. |
Edwards, S.W. and Knox, W.E. Homogentisate metabolism: the isomerization of maleylacetoacetate by an enzyme which requires glutathione. J. Biol. Chem. 220 (1956) 79–91. [PMID: 13319328] |
| 2. |
Lack, L. Enzymic cis-trans isomerization of maleylpyruvic acid. J. Biol. Chem. 236 (1961) 2835–2840. [PMID: 14461395] |
| 3. |
Seltzer, S. Purification and properties of maleylacetone cis-trans isomerase from Vibrio 01. J. Biol. Chem. 248 (1973) 215–222. [PMID: 4692831] |
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| [EC 5.2.1.2 created 1961] |
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