The Enzyme Database

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Accepted name: maleylacetoacetate isomerase
Reaction: 4-maleylacetoacetate = 4-fumarylacetoacetate
For diagram of tyrosine catabolism, click here
Other name(s): maleylacetoacetic isomerase; maleylacetone isomerase; maleylacetone cis-trans-isomerase
Systematic name: 4-maleylacetoacetate cis-trans-isomerase
Comments: Also acts on maleylpyruvate.
Links to other databases: BRENDA, EAWAG-BBD, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9023-75-0
1.  Edwards, S.W. and Knox, W.E. Homogentisate metabolism: the isomerization of maleylacetoacetate by an enzyme which requires glutathione. J. Biol. Chem. 220 (1956) 79–91. [PMID: 13319328]
2.  Lack, L. Enzymic cis-trans isomerization of maleylpyruvic acid. J. Biol. Chem. 236 (1961) 2835–2840. [PMID: 14461395]
3.  Seltzer, S. Purification and properties of maleylacetone cis-trans isomerase from Vibrio 01. J. Biol. Chem. 248 (1973) 215–222. [PMID: 4692831]
[EC created 1961]

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