Accepted name: α-methylacyl-CoA racemase
Reaction: (2S)-2-methylacyl-CoA = (2R)-2-methylacyl-CoA
Systematic name: 2-methylacyl-CoA 2-epimerase
Comments: α-methyl-branched acyl-CoA derivatives with chain lengths of more than C10 are substrates. Also active towards some aromatic compounds (e.g. ibuprofen) and bile acid intermediates, such as trihydroxycoprostanoyl-CoA. Not active towards free acids
1.  Schmitz, W., Fingerhut, R., Conzelmann, E. Purification and properties of an α-methylacyl-CoA racemase from rat liver. Eur. J. Biochem. 222 (1994) 313–323. [PMID: 8020470]
[EC created 1999]