| EC |
5.1.99.4 |
| Accepted name: |
α-methylacyl-CoA racemase |
| Reaction: |
(2S)-2-methylacyl-CoA = (2R)-2-methylacyl-CoA |
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For diagram of cholic acid biosynthesis (sidechain), click here |
| Systematic name: |
2-methylacyl-CoA 2-epimerase |
| Comments: |
α-methyl-branched acyl-CoA derivatives with chain lengths of more than C10 are substrates. Also active towards some aromatic compounds (e.g. ibuprofen) and bile acid intermediates, such as trihydroxycoprostanoyl-CoA. Not active towards free acids |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 156681-44-6 |
| References: |
| 1. |
Schmitz, W., Fingerhut, R., Conzelmann, E. Purification and properties of an α-methylacyl-CoA racemase from rat liver. Eur. J. Biochem. 222 (1994) 313–323. [DOI] [PMID: 8020470] |
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| [EC 5.1.99.4 created 1999] |
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