ExplorEnz: EC 5.1.3.33

Your query returned 1 entry. Printable version

5.1.3.33

Accepted name:

2-epi-5-epi-valiolone epimerase

Reaction:

2-epi-5-epi-valiolone = 5-epi-valiolone

For diagram of valiolone biosynthesis, click here

Glossary:

2-epi-5-epi-valiolone= (2S,3S,4S,5R)-2,3,4,5-tetrahydroxy-5-(hydroxymethyl)cyclohexanone
5-epi-valiolone = (2R,3S,4S,5R)-2,3,4,5-tetrahydroxy-5-(hydroxymethyl)cyclohexanone

Other name(s):

CetB; EVE

Systematic name:

2-epi-5-epi-valiolone 2-epimerase

Comments:

The enzyme, characterized from the bacterium Actinomyces sp. Lu 9419, is involved in the biosynthesis of the antitumor agent cetoniacytone A.

Links to other databases:

BRENDA, EXPASY, KEGG, MetaCyc

References:

1.	Wu, X., Flatt, P.M., Xu, H. and Mahmud, T. Biosynthetic gene cluster of cetoniacytone A, an unusual aminocyclitol from the endosymbiotic Bacterium Actinomyces sp. Lu 9419. ChemBioChem 10 (2009) 304–314. [DOI] [PMID: 19101977]

[EC 5.1.3.33 created 2015]