The Enzyme Database

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Accepted name: UDP-glucose 4-epimerase
Reaction: UDP-α-D-glucose = UDP-α-D-galactose
For diagram of UDP-glucose, UDP-galactose and UDP-glucuronate biosynthesis, click here
Other name(s): UDP-galactose 4-epimerase; uridine diphosphoglucose epimerase; galactowaldenase; UDPG-4-epimerase; uridine diphosphate galactose 4-epimerase; uridine diphospho-galactose-4-epimerase; UDP-glucose epimerase; 4-epimerase; uridine diphosphoglucose 4-epimerase; uridine diphosphate glucose 4-epimerase; UDP-D-galactose 4-epimerase
Systematic name: UDP-α-D-glucose 4-epimerase
Comments: Requires NAD+. Also acts on UDP-2-deoxyglucose.
Links to other databases: BRENDA, EXPASY, Gene, GTD, KEGG, MetaCyc, PDB, CAS registry number: 9032-89-7
1.  Leloir, L.F. Enzymic isomerization and related processes. Adv. Enzymol. Relat. Subj. Biochem. 14 (1953) 193–218. [PMID: 13057717]
2.  Maxwell, E.S. and de Robichon-Szulmajster, H. Purification of uridine diphosphate galactose-4-epimerase from yeast and the identification of protein-bound diphosphopyridine nucleotide. J. Biol. Chem. 235 (1960) 308–312.
3.  Wilson, D.B. and Hogness, D.S. The enzymes of the galactose operon in Escherichia coli. I. Purification and characterization of uridine diphosphogalactose 4-epimerase. J. Biol. Chem. 239 (1964) 2469–2481. [PMID: 14235524]
[EC created 1961]

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