The Enzyme Database

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Accepted name: CDP-paratose 2-epimerase
Reaction: CDP-α-D-paratose = CDP-α-D-tyvelose
For diagram of CDP-abequose, CDP-ascarylose, CDP-paratose and CDP-tyrelose biosynthesis, click here
Glossary: CDP-α-D-tyvelose = CDP-3,6-dideoxy-α-D-mannose = CDP-3,6-dideoxy-α-D-arabino-hexose
CDP-α-D-paratose = CDP-3,6-dideoxy-α-D-glucose = CDP-3,6-dideoxy-α-D-ribo-hexose
Other name(s): CDP-paratose epimerase; cytidine diphosphoabequose epimerase; cytidine diphosphodideoxyglucose epimerase; cytidine diphosphoparatose epimerase; cytidine diphosphate paratose-2-epimerase; CDP-abequose epimerase (incorrect); CDP-D-abequose 2-epimerase (incorrect); CDP-tyvelose 2-epimerase,
Systematic name: CDP-3,6-dideoxy-D-glucose 2-epimerase
Comments: Requires NAD+.
Links to other databases: BRENDA, EXPASY, GTD, KEGG, MetaCyc, PDB, CAS registry number: 37318-36-8
1.  Matsuhashi, S. Enzymatic synthesis of cytidine diphosphate 3,6-dideoxyhexoses. II. Reversible 2-epimerization of cytidine diphosphate paratose. J. Biol. Chem. 241 (1966) 4275–4282. [PMID: 5924649]
2.  Liu, H.-W. and Thorson, J.S. Pathways and mechanisms in the biogenesis of novel deoxysugars by bacteria. Annu. Rev. Microbiol. 48 (1994) 223–256. [DOI] [PMID: 7826006]
3.  Koropatkin, N.M., Liu, H.W. and Holden, H.M. High resolution x-ray structure of tyvelose epimerase from Salmonella typhi. J. Biol. Chem. 278 (2003) 20874–20881. [DOI] [PMID: 12642575]
[EC created 1972, modified 2005]

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