ExplorEnz: EC 5.1.1.26

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5.1.1.26

Accepted name:

cysteate racemase

Reaction:

L-cysteate = D-cysteate

Other name(s):

cuyB (gene name); cysteic acid racemase

Systematic name:

cysteate racemase

Comments:

The enzyme, characterized from the bacteria Bilophila wadsworthia and Ruegeria pomeroyi, participates in L-cysteate degradation.

Links to other databases:

BRENDA, EXPASY, KEGG, MetaCyc

References:

1.	Burchill, L., Stewart, A.WE., Pallasdies, L., Lee, M., Coe, L.SY., Zudich, L., Jebeli, L., Sharma, M., Hofferek, V., McConville, M.J., Davies, G.J., Scott, N.E., Durham, B.P. and Williams, S.J. Bridging a gap in marine sulfur cycling: discovery of a D-cysteinolic acid degradation pathway. J. Am. Chem. Soc. 147 (2025) 47934–47941. [DOI] [PMID: 41404639]
2.	Liu, C., Ma, K., Jiang, L., Liu, X., Tong, Y., Yang, S., Jin, X., Wei, Y. and Zhang, Y. Bacterial cysteate dissimilatory pathway involves a racemase and D-cysteate sulfo-lyase. J. Biol. Chem. 300:107371 (2024). [DOI] [PMID: 38750791]

[EC 5.1.1.26 created 2026]