The Enzyme Database

Your query returned 1 entry.    printer_iconPrintable version

Accepted name: L-Ala-D/L-Glu epimerase
Reaction: L-alanyl-D-glutamate = L-alanyl-L-glutamate
Other name(s): YkfB; YcjG; AEE; AE epimerase
Systematic name: L-alanyl-D-glutamate epimerase
Comments: The enzyme, characterized from the bacteria Escherichia coli and Bacillus subtilis, is involved in the recycling of the murein peptide, of which L-Ala-D-Glu is a component. In vitro the enzyme from Escherichia coli epimerizes several L-Ala-L-X dipeptides with broader specificity than the enzyme from Bacillus subtilis.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
1.  Schmidt, D.M., Hubbard, B.K. and Gerlt, J.A. Evolution of enzymatic activities in the enolase superfamily: functional assignment of unknown proteins in Bacillus subtilis and Escherichia coli as L-Ala-D/L-Glu epimerases. Biochemistry 40 (2001) 15707–15715. [DOI] [PMID: 11747447]
2.  Gulick, A.M., Schmidt, D.M., Gerlt, J.A. and Rayment, I. Evolution of enzymatic activities in the enolase superfamily: crystal structures of the L-Ala-D/L-Glu epimerases from Escherichia coli and Bacillus subtilis. Biochemistry 40 (2001) 15716–15724. [DOI] [PMID: 11747448]
[EC created 2015]

Data © 2001–2022 IUBMB
Web site © 2005–2022 Andrew McDonald