| EC |
4.8.1.6 |
| Accepted name: |
N-(sulfonatooxy)alkenimidothioic acid sulfate-lyase (epithionitrile-forming) |
| Reaction: |
N-(sulfonatooxy)alkenimidothioic acid with a terminal double bond = an epithionitrile + sulfate |
| Other name(s): |
ESP (gene name); epithionitrile-specifier protein; epithiospecifier protein |
| Systematic name: |
N-(sulfonatooxy)alkenimidothioic acid sulfate-lyase (epithionitrile-forming) |
| Comments: |
The enzyme is involved in the breakdown of glucosinolates. It acts only on aliphatic N-(sulfonatooxy)alkenimidothioic acids produced from ω-alkenyl-glucosinolates, and forms epithionitrile-containing products. cf. EC 4.8.1.5, thiohydroximate-O-sulfate sulfate/sulfur-lyase (nitrile-forming), and EC 4.8.1.7, phenyl-N-(sulfonatooxy)methanimidothioate sulfolyase. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Lambrix, V., Reichelt, M., Mitchell-Olds, T., Kliebenstein, D.J. and Gershenzon, J. The Arabidopsis epithiospecifier protein promotes the hydrolysis of glucosinolates to nitriles and influences Trichoplusia ni herbivory. Plant Cell 13 (2001) 2793–2807. [DOI] [PMID: 11752388] |
| 2. |
Zabala M. de, T., Grant, M., Bones, A.M., Bennett, R., Lim, Y.S., Kissen, R. and Rossiter, J.T. Characterisation of recombinant epithiospecifier protein and its over-expression in Arabidopsis thaliana. Phytochemistry 66 (2005) 859–867. [DOI] [PMID: 15845404] |
|
| [EC 4.8.1.6 created 2022] |
| |
|
| |
|
Printable version