EC |
4.4.1.40 |
Accepted name: |
C-phycoerythrin β-cysteine-48/59 phycoerythrobilin lyase |
Reaction: |
a [C-phycoerythrin β-subunit]-Cys48/59-phycoerythrobilin = apo-[C-phycoerythrin β-subunit] + (3E)-phycoerythrobilin |
Other name(s): |
cpeF (gene name) |
Systematic name: |
[C-phycoerythrin β-subunit]-Cys48/59-phycoerythrobilin:phycoerythrobilin lyase |
Comments: |
The enzyme, characterized from the cyanobacterium Microchaete diplosiphon, catalyses the attachment of the phycobilin chromophore (3E)-phycoerythrobilin (PEB) to cysteine 48 and 59 of the β subunits of the phycobiliprotein C-phycoerythrin. The enzyme first ligates the A ring of PEB to cysteine-48, followed by the attachment of the D ring to cysteine-59. The numbering used here corresponds to the enzyme from Microchaete diplosiphon, and could vary slightly in other organisms. The reaction requires the presence of the chaperone-like protein CpeZ. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Kronfel, C.M., Hernandez, C.V., Frick, J.P., Hernandez, L.S., Gutu, A., Karty, J.A., Boutaghou, M.N., Kehoe, D.M., Cole, R.B. and Schluchter, W.M. CpeF is the bilin lyase that ligates the doubly linked phycoerythrobilin on β-phycoerythrin in the cyanobacterium Fremyella diplosiphon. J. Biol. Chem. 294 (2019) 3987–3999. [DOI] [PMID: 30670589] |
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[EC 4.4.1.40 created 2021] |
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