|
Your query returned 1 entry. Printable version
EC | 4.4.1.20 | ||||||||
Accepted name: | leukotriene-C4 synthase | ||||||||
Reaction: | leukotriene C4 = leukotriene A4 + glutathione | ||||||||
For diagram of leukotriene biosynthesis, click here | |||||||||
Glossary: | leukotriene C4 = (7E,9E,11Z,14Z)-(5S,6R)-6-(glutathion-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate leukotriene A4 = (7E,9E,11Z,14Z)-(5S,6S)-5,6-epoxyicosa-7,9,11,14-tetraenoate |
||||||||
Other name(s): | leukotriene C4 synthetase; LTC4 synthase; LTC4 synthetase; leukotriene A4:glutathione S-leukotrienyltransferase; (7E,9E,11Z,14Z)-(5S,6R)-5,6-epoxyicosa-7,9,11,14-tetraenoate:glutathione leukotriene-transferase (epoxide-ring-opening); (7E,9E,11Z,14Z)-(5S,6R)-6-(glutathion-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate glutathione-lyase (epoxide-forming) | ||||||||
Systematic name: | leukotriene-C4 glutathione-lyase (leukotriene-A4-forming) | ||||||||
Comments: | The reaction proceeds in the direction of addition. Not identical with EC 2.5.1.18, glutathione transferase. | ||||||||
Links to other databases: | BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 90698-32-1 | ||||||||
References: |
| ||||||||