The Enzyme Database

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Accepted name: choline trimethylamine-lyase
Reaction: choline = trimethylamine + acetaldehyde
Other name(s): cutC (gene name)
Systematic name: choline trimethylamine-lyase (acetaldehyde-forming)
Comments: The enzyme utilizes a glycine radical to break the C-N bond in choline. Found in choline-degrading anaerobic bacteria.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB
1.  Craciun, S. and Balskus, E.P. Microbial conversion of choline to trimethylamine requires a glycyl radical enzyme. Proc. Natl. Acad. Sci. USA 109 (2012) 21307–21312. [DOI] [PMID: 23151509]
[EC created 2013]

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