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Your query returned 1 entry. 
Printable version
| EC | 4.3.3.8 | ||||||||
| Accepted name: | mimosinase | ||||||||
| Reaction: | L-mimosine + H2O = 3-hydroxy-4H-pyrid-4-one + pyruvate + NH3 (overall reaction) (1a) L-mimosine = 3-hydroxy-4H-pyrid-4-one + 2-aminoprop-2-enoate (1b) 2-aminoprop-2-enoate = 2-iminopropanoate (spontaneous) (1c) 2-iminopropanoate + H2O = pyruvate + NH3 (spontaneous) |
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| Glossary: | L-mimosine = (2S)-2-amino-3-[3-hydroxy-4-oxopyridin-1(4H)-yl]propanoate | ||||||||
| Other name(s): | mimosine amidohydrolase (incorrect) | ||||||||
| Systematic name: | (2S)-2-amino-3-[3-hydroxy-4-oxopyridin-1(4H)-yl]propanoate 3-hydroxy-4H-pyrid-4-one-lyase (2-aminoprop-2-enoate-forming) | ||||||||
| Comments: | A pyridoxal 5′-phosphate protein. The enzyme degrades the toxic amino acid L-mimosine. It cleaves a carbon-nitrogen bond, releasing 3-hydroxy-4H-pyrid-4-one and an unstable enamine product that tautomerizes to an imine form, which undergoes a hydrolytic deamination to form pyruvate and ammonia. It is thought to have evolved from EC 4.4.1.13, cysteine-S-conjugate β-lyase. It has been described in both mimosine-producing plants and some bacteria. | ||||||||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 104118-49-2 | ||||||||
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