EC |
4.2.3.89 |
Accepted name: |
(+)-β-caryophyllene synthase |
Reaction: |
(2E,6E)-farnesyl diphosphate = (+)-β-caryophyllene + diphosphate |
|
For diagram of bicyclic and tricyclic sesquiterpenoids derived from humuladienyl cation, click here |
Other name(s): |
GcoA |
Systematic name: |
(2Z,6E)-farnesyl-diphosphate diphosphate-lyase [cyclizing, (+)-β-caryophyllene-forming] |
Comments: |
A multifunctional enzyme which also converts the (+)-β-caryophyllene to (+)-caryolan-1-ol (see EC 4.2.1.138, (+)-caryolan-1-ol synthase). cf. EC 4.2.3.57 (–)-β-caryophyllene synthase. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Nakano, C., Horinouchi, S. and Ohnishi, Y. Characterization of a novel sesquiterpene cyclase involved in (+)-caryolan-1-ol biosynthesis in Streptomyces griseus. J. Biol. Chem. 286 (2011) 27980–27987. [DOI] [PMID: 21693706] |
|
[EC 4.2.3.89 created 2011] |
|
|
|
|