The Enzyme Database

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Accepted name: 10-epi-γ-eudesmol synthase
Reaction: (2E,6E)-farnesyl diphosphate + H2O = 10-epi-γ-eudesmol + diphosphate
For diagram of eudesmol and selinene biosynthesis, click here and for diagram of eudesmol biosynthesis, click here
Glossary: 10-epi-γ-eudesmol = 2-[(2R,4aS)-4a,8-dimethyl-1,2,3,4,4a,5,6,7-octahydronaphthalen-2-yl]propan-2-ol
Systematic name: (2E,6E)-farnesyl-diphosphate diphosphate-lyase (10-epi-γ-eudesmol-forming)
Comments: The recombinant enzyme from ginger (Zingiber zerumbet) gives 62.6% β-eudesmol, 16.8% 10-epi-γ-eudesmol, 10% α-eudesmol, and 5.6% aristolene. cf. EC (β-eudesmol synthase) and EC (α-eudesmol synthase)
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
1.  Yu, F., Harada, H., Yamasaki, K., Okamoto, S., Hirase, S., Tanaka, Y., Misawa, N. and Utsumi, R. Isolation and functional characterization of a β-eudesmol synthase, a new sesquiterpene synthase from Zingiber zerumbet Smith. FEBS Lett. 582 (2008) 565–572. [DOI] [PMID: 18242187]
[EC created 2011]

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