EC |
4.2.3.70 |
Accepted name: |
patchoulol synthase |
Reaction: |
(2E,6E)-farnesyl diphosphate + H2O = patchoulol + diphosphate |
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For diagram of guaiene, α-gurjunene, patchoulol and viridiflorene biosynthesis, click here |
Systematic name: |
(2E,6E)-farnesyl-diphosphate diphosphate-lyase (patchoulol-forming) |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Croteau, R., Munck, S.L., Akoh, C.C., Fisk, H.J. and Satterwhite, D.M. Biosynthesis of the sesquiterpene patchoulol from farnesyl pyrophosphate in leaf extracts of Pogostemon cablin (patchouli): mechanistic considerations. Arch. Biochem. Biophys. 256 (1987) 56–68. [DOI] [PMID: 3038029] |
2. |
Munck, S.L. and Croteau, R. Purification and characterization of the sesquiterpene cyclase patchoulol synthase from Pogostemon cablin. Arch. Biochem. Biophys. 282 (1990) 58–64. [DOI] [PMID: 2171435] |
3. |
Faraldos, J.A., Wu, S., Chappell, J. and Coates, R.M. Doubly deuterium-labeled patchouli alcohol from cyclization of singly labeled [2-2H1]farnesyl diphosphate catalyzed by recombinant patchoulol synthase. J. Am. Chem. Soc. 132 (2010) 2998–3008. [DOI] [PMID: 20148554] |
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[EC 4.2.3.70 created 2011] |
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