The Enzyme Database

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EC 4.2.3.3     
Accepted name: methylglyoxal synthase
Reaction: glycerone phosphate = 2-oxopropanal + phosphate
Glossary: glycerone phosphate = dihydroxyacetone phosphate = 3-hydroxy-2-oxopropyl phosphate
2-oxopropanal = methylglyoxal
Other name(s): methylglyoxal synthetase; glycerone-phosphate phospho-lyase
Systematic name: glycerone-phosphate phosphate-lyase (methylglyoxal-forming)
Comments: Does not act on D-glyceraldehyde 3-phosphate.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 37279-01-9
References:
1.  Cooper, R.A. and Anderson, A. The formation and catabolism of methylglyoxal during glycolysis in Escherichia coli. FEBS Lett. 11 (1970) 273–276. [DOI] [PMID: 11945504]
2.  Hopper, D.J. and Cooper, R.A. The regulation of Escherichia coli methylglyoxal synthase; a new control site in glycolysis? FEBS Lett. 13 (1971) 213–216. [DOI] [PMID: 11945670]
3.  Ray, S. and Ray, M. Isolation of methylglyoxal synthase from goat liver. J. Biol. Chem. 256 (1981) 6230–6233. [PMID: 7240200]
[EC 4.2.3.3 created 1972 as EC 4.2.99.11, transferred 2000 to EC 4.2.3.3]
 
 


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