EC	4.2.3.211
Accepted name:	(+)-exo-β-bergamotene synthase
Reaction:	(2E,6E)-farnesyl diphosphate = (+)-exo-β-bergamotene + diphosphate
Glossary:	(+)-exo-β-bergamotene = β-trans-bergamotene = (1S,5S,6R)-6-methyl-2-methylidene-6-(4-methylpent-3-enyl)bicyclo[3.1.1]heptane fumagillin = (2E,4E,6E,8E)-10-({(3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl]-1-oxaspiro[2.5]oct-6-yl}oxy)-10-oxodeca-2,4,6,8-tetraenoate
Systematic name:	(2E,6E)-farnesyl-diphosphate diphosphate-lyase [(+)-exo-β-bergamotene-forming]
Comments:	The enzyme, characterized from the mold Aspergillus fumigatus, participates in the biosynthesis of the meroterpenoid fumagillin.
References:	1.  Lin, H.C., Chooi, Y.H., Dhingra, S., Xu, W., Calvo, A.M. and Tang, Y. The fumagillin biosynthetic gene cluster in Aspergillus fumigatus encodes a cryptic terpene cyclase involved in the formation of β-trans-bergamotene. J. Am. Chem. Soc. 135 (2013) 4616–4619. [PMID: 23488861]
[EC 4.2.3.211 created 2022]