ExplorEnz: EC 4.2.3.208

4.2.3.208

Accepted name:

verrucosan-2β-ol synthase

Reaction:

geranylgeranyl diphosphate + H₂O = verrucosan-2β-ol + diphosphate

Glossary:

verrucosan-2β-ol = (1S,3aR,5aS,6aR,7aR,8S,8aR,9bR)-1-(propan=2-yl)tetradecahydrocyclopenta[a]cyclopropa[g]naphthalene-8-ol

Other name(s):

ChlTC2

Systematic name:

geranylgeranyl-diphosphate diphosphate-lyase (verrucosan-2β-ol-forming)

Comments:

Requires Mg²⁺. Characterized from the bacterium Chloroflexus aurantiacus.

References:

1.	Yang, Y.L., Zhang, S., Ma, K., Xu, Y., Tao, Q., Chen, Y., Chen, J., Guo, S., Ren, J., Wang, W., Tao, Y., Yin, W.B. and Liu, H. Discovery and characterization of a new family of diterpene cyclases in bacteria and fungi. Angew. Chem. Int. Ed. Engl. 56 (2017) 4749–4752. [PMID: 28371074]

[EC 4.2.3.208 created 2022]