Accepted name: α-isocomene synthase
Reaction: (2E,6E)-farnesyl diphosphate = (-)-α-isocomene + diphosphate
Glossary: (-)-α-isocomene = (1R,3aS,5aS,8aR)-1,3a,4,5a-tetramethyl-1,2,3,3a,5a,6,7,8-octahydrocyclopenta[c]pentalene
Other name(s): MrTPS2
Systematic name: (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, (-)-α-isocomene-forming)
Comments: Isolated from the roots of the plant Matricaria chamomilla var. recutita (chamomile). The enzyme also produced traces of five other sesquiterpenoids.
1.  Irmisch, S., Krause, S.T., Kunert, G., Gershenzon, J., Degenhardt, J. and Kollner, T.G. The organ-specific expression of terpene synthase genes contributes to the terpene hydrocarbon composition of chamomile essential oils. BMC Plant Biol. 12:84 (2012). [PMID: 22682202]
[EC created 2012]

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