| EC |
4.2.3.133 |
| Accepted name: |
α-copaene synthase |
| Reaction: |
(2E,6E)-farnesyl diphosphate = (-)-α-copaene + diphosphate |
| Glossary: |
(-)-α-copaene = (1R,2S,6S,7S,8S)-1,3-dimethyl-8-(propan-2-yl)tricyclo[4.4.0.02,7]dec-3-ene
For diagram of the structures of α-copaene and β-copaene, click here |
| Systematic name: |
(2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, α-copaene-forming) |
| Comments: |
Isolated from Helianthus annuus (sunflower). The enzyme also produces β-caryophyllene, δ-cadinene and traces of other sesquiterpenoids. See EC 4.2.3.13 (+)-δ-cadinene synthase, EC 4.2.3.57 (-)-β-caryophyllene synthase. |
| References: |
| 1. |
Gopfert, J.C., Macnevin, G., Ro, D.K. and Spring, O. Identification, functional characterization and developmental regulation of sesquiterpene synthases from sunflower capitate glandular trichomes. BMC Plant Biol. 9:86 (2009). [PMID: 19580670] |
| 2. |
Xie, X., Kirby, J. and Keasling, J.D. Functional characterization of four sesquiterpene synthases from Ricinus communis (castor bean). Phytochemistry 78 (2012) 20–28. [PMID: 22459969] |
|
| [EC 4.2.3.133 created 2012] |
| |
|
| |
|