The Enzyme Database

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Accepted name: (+)-δ-cadinene synthase
Reaction: (2E,6E)-farnesyl diphosphate = (+)-δ-cadinene + diphosphate
For diagram of cadinane sesquiterpenoid biosynthesis, click here and for diagram of cadinene, cubebol and muuroladiene biosynthesis, click here
Systematic name: (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, (+)-δ-cadinene-forming)
Comments: The sesquiterpenoid (+)-δ-cadinene is an intermediate in phytoalexin biosynthesis. Mg2+ is required for activity.
Links to other databases: BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 166800-09-5
1.  Chen, X.-Y., Chen, Y., Heinstein, P., Davisson, V.J. Cloning, expression and characterization of (+)-δ-cadinene synthase: a catalyst for cotton phytoalexin biosynthesis. Arch. Biochem. Biophys. 324 (1995) 255–266. [DOI] [PMID: 8554317]
2.  Davis, E.M., Tsuji, J., Davis, G.D., Pierce, M.L., Essenberg, M. Purification of (+)-δ-cadinene synthase, a sesquiterpene cyclase from bacteria-inoculated cotton foliar tissue. Phytochemistry 41 (1996) 1047–1055. [DOI] [PMID: 8728715]
3.  Davis, G.D., Essenberg, M. (+)-δ-Cadinene is a product of sesquiterpene cyclase activity in cotton. Phytochemistry 39 (1995) 553–567.
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