The Enzyme Database

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Accepted name: α-humulene synthase
Reaction: (2E,6E)-farnesyl diphosphate = α-humulene + diphosphate
For diagram of sesquiterpenoid biosynthesis based on humulene, click here
Other name(s): ZSS1
Systematic name: (2E,6E)-farnesyl-diphosphate diphosphate-lyase (α-humulene-forming)
Comments: The enzyme from Zingiber zerumbet, shampoo ginger, also gives traces of β-caryophyllene.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
1.  Yu, F., Okamto, S., Nakasone, K., Adachi, K., Matsuda, S., Harada, H., Misawa, N. and Utsumi, R. Molecular cloning and functional characterization of α-humulene synthase, a possible key enzyme of zerumbone biosynthesis in shampoo ginger (Zingiber zerumbet Smith). Planta 227 (2008) 1291–1299. [DOI] [PMID: 18273640]
[EC created 2012]

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