| EC |
4.2.3.100 |
| Accepted name: |
bicyclogermacrene synthase |
| Reaction: |
(2E,6E)-farnesyl diphosphate = bicyclogermacrene + diphosphate |
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For diagram of bicyclogermacrene and avermitilol biosynthesis, click here |
| Other name(s): |
Ov-TPS4 |
| Systematic name: |
(2E,6E)-farnesyl-diphosphate diphosphate-lyase (bicyclogermacrene-forming) |
| Comments: |
The enzyme from oregano (Origanum vulgare) gives mainly bicyclogermacrene with Mn2+ as a cofactor. With Mg2+ a more complex mixture is produced. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Crocoll, C., Asbach, J., Novak, J., Gershenzon, J. and Degenhardt, J. Terpene synthases of oregano (Origanum vulgare L.) and their roles in the pathway and regulation of terpene biosynthesis. Plant Mol. Biol. 73 (2010) 587–603. [DOI] [PMID: 20419468] |
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| [EC 4.2.3.100 created 2012] |
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