| EC |
4.2.1.77 |
| Accepted name: |
trans-L-3-hydroxyproline dehydratase |
| Reaction: |
trans-3-hydroxy-L-proline = 1-pyrroline 2-carboxylate + H2O |
| Other name(s): |
trans-L-3-hydroxyproline hydro-lyase |
| Systematic name: |
trans-3-hydroxy-L-proline hydro-lyase (1-pyrroline-2-carboxylate-forming) |
| Comments: |
Highly specific. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Ramaswamy, S.G. Conversion of 3-hydroxyproline to proline in the rat requires reduced pyridine-nucleotides. Fed. Proc. 42 (1983) 2232. |
| 2. |
Visser, W.F., Verhoeven-Duif, N.M. and de Koning, T.J. Identification of a human trans-3-hydroxy-L-proline dehydratase, the first characterized member of a novel family of proline racemase-like enzymes. J. Biol. Chem. 287 (2012) 21654–21662. [DOI] [PMID: 22528483] |
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| [EC 4.2.1.77 created 1984] |
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