| EC |
4.2.1.6 |
| Accepted name: |
galactonate dehydratase |
| Reaction: |
D-galactonate = 2-dehydro-3-deoxy-D-galactonate + H2O |
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For diagram of the Entner-Doudoroff pathway, click here |
| Other name(s): |
D-galactonate dehydrase; D-galactonate dehydratase; D-galactonate hydro-lyase |
| Systematic name: |
D-galactonate hydro-lyase (2-dehydro-3-deoxy-D-galactonate-forming) |
| Comments: |
The enzyme shows no activity with D-gluconate [2]. cf. EC 4.2.1.140, gluconate/galactonate dehydratase. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 9024-38-8 |
| References: |
| 1. |
De Ley, J. and Doudoroff, M. The metabolism of D-galactose in Pseudomonas saccharophila. J. Biol. Chem. 227 (1957) 745–757. [PMID: 13462997] |
| 2. |
Donald, A., Sibley, D., Lyons, D.E. and Dahms, A.S. D-Galactonate dehydrase. Purification and properties. J. Biol. Chem. 254 (1979) 2132–2137. [PMID: 422572] |
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| [EC 4.2.1.6 created 1961] |
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