Accepted name: gluconate dehydratase
Reaction: D-gluconate = 2-dehydro-3-deoxy-D-gluconate + H2O
Other name(s): D-gluconate dehydratase; D-gluconate hydro-lyase
Systematic name: D-gluconate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming)
Comments: The enzyme shows no activity with D-galactonate [2]. cf. EC, gluconate/galactonate dehydratase.
1.  Andreesen, J.R. and Gottschalk, G. The occurrence of a modified Entner-Doudoroff pathway in Clostridium aceticum. Arch. Mikrobiol. 69 (1969) 160–170. [PMID: 5383859]
2.  Bender, R. and Gottschalk, G. Purification and properties of D-gluconate dehydratase from Clostridium pasteurianum. Eur. J. Biochem. 40 (1973) 309–321. [PMID: 4772682]
[EC created 1972]