The Enzyme Database

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EC 4.2.1.30     
Accepted name: glycerol dehydratase
Reaction: glycerol = 3-hydroxypropanal + H2O
Other name(s): glycerol dehydrase; glycerol hydro-lyase; dhaB (gene name)
Systematic name: glycerol hydro-lyase (3-hydroxypropanal-forming)
Comments: Two different forms of the enzyme have been described. One form requires a cobamide coenzyme, while the other is a glycyl radical enzyme.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 9077-68-3
References:
1.  Smiley, K.L. and Sobolov, M. A cobamide-requiring glycerol dehydrase from an acrolein-forming Lactobacillus. Arch. Biochem. Biophys. 97 (1962) 538–543. [DOI] [PMID: 14039344]
2.  Schneider, Z. and Pawelkiewicz, J. The properties of glycerol dehydratase isolated from Aerobacter aerogenes, and the properties of the apoenzyme subunits. Acta Biochim. Pol. 13 (1966) 311–328. [PMID: 5962440]
3.  Schneider, Z., Larsen, E.G., Jacobsen, G., Johnson, B.C. and Pawelkiewicz, J. Purification and properties of glycerol dehydrase. J. Biol. Chem. 245 (1970) 3388–3396. [PMID: 4989992]
4.  Forage, R.G. and Foster, M.A. Glycerol fermentation in Klebsiella pneumoniae: functions of the coenzyme B12-dependent glycerol and diol dehydratases. J. Bacteriol. 149 (1982) 413–419. [PMID: 7035429]
5.  O'Brien, J.R., Raynaud, C., Croux, C., Girbal, L., Soucaille, P. and Lanzilotta, W.N. Insight into the mechanism of the B12-independent glycerol dehydratase from Clostridium butyricum: preliminary biochemical and structural characterization. Biochemistry 43 (2004) 4635–4645. [PMID: 15096031]
[EC 4.2.1.30 created 1972]
 
 


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