The Enzyme Database

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EC 4.2.1.180     
Accepted name: (E)-benzylidenesuccinyl-CoA hydratase
Reaction: (R,S)-2-(α-hydroxybenzyl)succinyl-CoA = (E)-benzylidenesuccinyl-CoA + H2O
Other name(s): bbsH (gene name)
Systematic name: (R,S)-2-(α-hydroxybenzyl)succinyl-CoA hydro-lyase
Comments: The enzyme, purified from the bacterium Thauera aromatica, is involved in an anaerobic toluene degradation pathway in which it catalyses the hydration of (E)-benzylidenesuccinyl-CoA.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  von Horsten, S., Lippert, M.L., Geisselbrecht, Y., Schuhle, K., Schall, I., Essen, L.O. and Heider, J. Inactive pseudoenzyme subunits in heterotetrameric BbsCD, a novel short-chain alcohol dehydrogenase involved in anaerobic toluene degradation. FEBS J. (2021) . [DOI] [PMID: 34601806]
[EC 4.2.1.180 created 2022]
 
 


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