The Enzyme Database

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Accepted name: phosphopyruvate hydratase
Reaction: 2-phospho-D-glycerate = phosphoenolpyruvate + H2O
For diagram of the Entner-Doudoroff pathway, click here
Other name(s): enolase; 2-phosphoglycerate dehydratase; 14-3-2-protein; nervous-system specific enolase; phosphoenolpyruvate hydratase; 2-phosphoglycerate dehydratase; 2-phosphoglyceric dehydratase; 2-phosphoglycerate enolase; γ-enolase; 2-phospho-D-glycerate hydro-lyase
Systematic name: 2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming)
Comments: Also acts on 3-phospho-D-erythronate.
Links to other databases: BRENDA, EXPASY, GTD, KEGG, MetaCyc, PDB, CAS registry number: 9014-08-8
1.  Holt, A. and Wold, F. The isolation and characterization of rabbit muscle enolase. J. Biol. Chem. 236 (1961) 3227–3231. [PMID: 13908561]
2.  Malmström, B.G. Enolase. In: Boyer, P.D., Lardy, H. and Myrbäck, K. (Ed.), The Enzymes, 2nd edn, vol. 5, Academic Press, New York, 1961, pp. 471–494.
3.  Westhead, E.W. and McLain, G. Purification of brewers’ and bakers’ yeast enolase yielding a single active component. J. Biol. Chem. 239 (1964) 2464–2468. [PMID: 14235523]
[EC created 1961]

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